Tylenol 8 Hour Arthritis delivers 650 mg of acetaminophen in each caplet, providing extended release pain relief through its unique bi-layer caplet design. When considering joint & muscle pain relief medications, rely on Tylenol. These pain relief caplets work for up to 8 hours but won’t irritate your stomach the way ibuprofen can. Turn to Tylenol for backache, muscular aches & pains, and minor arthritis pain. This is the Number 1 Doctor Recommended OTC brand for arthritis pain* and a sponsor of the National Arthritis Foundation. Tylenol takes your pain seriously. *Based on a Survey of Doctors (IQVIA 2025)
